Influenza Guide

About Influenza

Influenza is a potentially fatal disease that is estimated to cause up to 100 deaths and 5,100 hospitalisations in Australia annually.^[1] However, these figures are likely to under-represent the real burden of influenza in Australia.

Healthcare professionals have an important role in prompting patients to consider the benefits of influenza vaccination and addressing concerns about its efficacy and safety.

This guide provides useful information about influenza and vaccination, along with tips on how to facilitate influenza vaccination programs in general practice.

Provider Resources For First Nations Peoples

First Nations peoples are more likely to experience severe influenza. The influenza vaccine is available for all First Nations peoples under the National Immunisation Program (NIP).

New resources are available to help providers talk to First Nations peoples about influenza vaccinations.

Influenza And The NIP

Timing Of Vaccinations

Vaccination is encouraged before and throughout the influenza season. In Australia, the influenza season is officially recognised as starting in April. However, residents of northern Australia should be offered the new seasonal vaccines as soon as they become available. This also applies to your patients during their pregnancy. 

Optimal protection against influenza occurs in the first 3 to 4 months after vaccination.^[3]

2025 Influenza Vaccines Available For Use In Australia

Discard 2024 influenza vaccines where possible as these are not manufactured to the latest seasonal influenza virus. 

Remember to discard the prior year’s influenza vaccine unless there is a good reason and they are still in date.

Seasonal influenza vaccines available for use in Australia in 2025, by age:^[2] 

✔  Ticks indicate the ages at which a vaccine is registered and available

*   Vaccine is funded under the NIP for eligible people
** NIP funding only for Aboriginal and/or Torres Strait Islander people, pregnant people, and people who have certain medical conditions
X   Vaccine is not available for that age group

^[#] cell-based vaccine

Influenza And COVID-19

COVID-19 and influenza are both serious respiratory infections. It is therefore essential that patients are immunised against influenza at the earliest opportunity, particularly those most at risk.

All COVID-19 vaccines can be co-administered with an influenza vaccine.^[3]

Influenza And Pregnancy

Influenza is a potentially severe disease that can affect both the birthing parent and baby. It can affect the birthing parent in the second and third trimesters and the baby in the first few months after birth, even causing death.

Read more about influenza vaccination while pregnant here.

Influenza And Children

The influenza vaccination is funded under the NIP for children aged between 6 months and <5 years for some vaccines. The vaccines available for children under the NIP in this age group are:

• Vaxigrip Tetra® 0.5mL  (6 months to <5 years)
• FluQuadri® 0.5mL (6 months to <5 years)

NIP Funded Influenza vaccines for Aboriginal and/or Torres Strait Islander children and people who have certain medical conditions:

• Flucelvax®Quad 0.5mL (from 5 years and older)
• Vaxigrip Tetra® 0.5mL (from 5 years and older)
  

Other vaccines that are registered and available for children in 2025 but are not funded under the NIP are:

• Influvac®Tetra 0.5mL (all ages)
• Afluria®Quad 0.5mL  (5 years and older)
• FluQuadri® 0.5mL (5 years and older)
• Flucelvax®Quad 0.5mL (6 months and older)

Enhanced Influenza Vaccines For Older People

There are 2 enhanced influenza vaccines available for older adults in 2025:

• Fluad® Quad 0.5mL for people aged 65 and over (funded under the NIP)
• Fluzone® High-Dose Quad 0.7 mL for people aged 60 and over (not funded under the NIP)

For adults aged 65 and over, either the adjuvanted influenza vaccine (Fluad Quad, funded under the NIP) or the high-dose influenza vaccine (Fluzone High Dose Quadrivalent) is recommended over standard-dose egg-based or cell-based influenza vaccines.^[4]

Influenza and Heart Attacks

Evidence from several studies indicates that annual vaccination against seasonal influenza reduces cardiovascular morbidity and mortality in patients with cardiovascular conditions. Studies suggest that the influenza vaccine almost halves the risk of heart attacks in older adults.^[4][5]

GPs who treat individuals with cardiovascular disease can help improve influenza vaccination coverage rates by asking about vaccination status, strongly recommending it, and providing vaccination to their patients before and throughout the influenza season.

Co-Administration With Other Vaccines

Influenza vaccines can be administered at the same time as, or at any interval before or after, other vaccines. This includes dTPa, respiratory syncytial virus (RSV), pneumococcal, and COVID-19 vaccines.^[1]